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Scientists have discovered a swifter and more precise way to edit the genome of immune cells, opening doors for cancer and HIV therapies.
Researchers drew immune cells from people on effective HIV treatment, cultured the cells and reinfused 40 million of them.
Such latently infected cells remain under the radar of antiretroviral treatment, which only works on replicating cells.
Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.
This is according to an analysis of pooled data from various studies looking at those who controlled HIV after stopping treatment.
A speedy overview of the major scientific findings presented at the International AIDS Conference in Amsterdam (AIDS 2018)
The “kick-and-kill” strategy—waking up latently infected immune cells so as to kill them—did not reduce participants’ viral DNA.
This disappointment highlights the challenge of translating animal research into human trials.
Understanding the importance of basic HIV research and clinical trials—and the benefits of being undetectable
Findings provide reassurance on ethics of cure studies.
Scientists found this receptor on the CD4 cells of so-called elite controllers of the virus.
Take a survey on HIV cure research.
It’s just one episode of “HIV Matters,” a (free!) podcast series from the University of North Carolina’s Department of Medicine.
A recent study found that agents used to wake up resting HIV-infected cells probably work only on 5 percent of such cells.
Scientists tested the effects of the broadly neutralizing antibody PGT121 and the immune-stimulating agent GS-9620 in monkeys.
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